Association of TP53 Arg72Pro polymorphism (rs1042522) with bladder cancer risk in the Ukrainian population
نویسندگان
چکیده
منابع مشابه
the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولAssociation between the rs1042522 polymorphism in TP53 and prostate cancer risk: An updated meta-analysis
OBJECTIVE The proposal of the present study was to investigate whether the TP53 rs1042522 polymorphism confers susceptibility to prostate cancer (PCa), by performing an updated meta-analysis. METHODS Eligible publications investigating the association between the TP53 rs1042522 polymorphism and PCa susceptibility were selected from PubMed, Google Scholar, and Web of Science. We used STATA 12....
متن کاملAssociation between TP53 gene Arg72Pro polymorphism and Wilms’ tumor risk in a Chinese population
Wilms' tumor is one of the most prevalent pediatric malignancies, ranking fourth in childhood cancer worldwide. TP53 is a critical tumor suppressor gene, which encodes a 53 kDa protein, p53. The p53 functions to protect against cancer by regulating cell cycle and apoptosis and maintaining DNA integrity. TP53 gene is highly polymorphic. Several TP53 gene polymorphisms have been considered to be ...
متن کاملAssociation of Arg72Pro of P53 polymorphism with colorectal cancer susceptibility risk in Malaysian population.
BACKGROUND Colorectal cancer (CRC) results from the interaction between environmental exposures and genetic predisposition factors. AIMS A case control study was designed and to investigate the genotype frequencies of P53Arg72Pro polymorphism in Malaysian CRC patients and healthy controls and to determine the associated risk of this polymorphism with CRC predisposition. METHODS In this case...
متن کاملNo association between TP53 Arg72Pro polymorphism and ovarian cancer risk: evidence from 10113 subjects
The TP53 gene product is an important regulator of cell growth and a tumor suppressor. The association between TP53 Arg72Pro polymorphism and ovarian cancer risk has been widely investigated, but the results are contradictory. We therefore searched the PubMed, EMBASE and Chinese Biomedical databases for studies on the relation between TP53 Arg72Pro polymorphism and ovarian cancer risk. Our fina...
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ژورنال
عنوان ژورنال: Faktori eksperimental'noi evolucii organizmiv
سال: 2018
ISSN: 2415-3826,2219-3782
DOI: 10.7124/feeo.v23.1017